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 — Manganese-enhanced magnetic resonance imaging (MEMRI) without compromise of the blood–brain barrier detects hypothalamic neuronal activityin vivo December 2006 NMR in Biomedicine 19(8):1028-34

 — In this study a manganese-enhanced magnetic resonance imaging (MEMRI) method was developed for mice for measuring axonal transport (AXT) rates in real time in olfactory receptor neurons, which project from the olfactory epithelium to the olfactory neuronal layer of the olfactory bulb. Using this MEM …

In Vivo Tracking of Transplanted Mononuclear Cells Using Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) Kenichi Odaka1, Ichio Aoki1*, Junji Moriya2, Kaoru Tateno2, Hiroyuki Tadokoro3, Jeff Kershaw1, Tohru Minamino2, Toshiaki Irie1, Toshimitsu Fukumura1, Issei Komuro2, Tsuneo Saga1 1 Molecular Imaging Center, National …

 — Manganese-enhanced MRI (MEMRI) is being increasingly used for MRI in animals due to the unique T 1 contrast that is sensitive to a number of biological processes. Three specific uses of MEMRI have …

 — In Vivo Tracking of Transplanted Mononuclear Cells Using Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) Kenichi Odaka, 1 Ichio Aoki, 1, * Junji Moriya, 2 Kaoru Tateno, 2 Hiroyuki Tadokoro, 3 Jeff Kershaw, 1 Tohru Minamino, 2 Toshiaki Irie, 1 Toshimitsu Fukumura, 1 Issei Komuro, 2 and Tsuneo Saga 1

 — Manganese-enhanced magnetic resonance imaging (MEMRI) relies on the strong paramagnetism of Mn 2+.Mn 2+ is a calcium ion analog and can enter excitable cells through voltage-gated calcium channels. Mn 2+ can be transported along the axons of neurons via microtubule-based fast axonal transport. Based on these properties, MEMRI …

In vivo, trans-synaptic tract-tracing utilizing manganese-enhanced magnetic resonance imaging (MEMRI) NMR Biomed. 2004 Dec;17(8):595-601. doi: 10.1002/nbm.942. Author Robia G Pautler 1 Affiliation 1 Department of Molecular Physiology ... Magnetic Resonance Imaging / methods*

In vivo manganese-enhanced magnetic resonance imaging reveals connections and functional properties of the songbird vocal control system. Neuroscience 2002; 112: 467–474. 14. Saleem KS, Pauls JM, Augath M, Trinath T, Prause BA, Hashikawa T, Logothetis NK. Magnetic resonance imaging of neuronal connections in the macaque …

 — In vivo, trans-synaptic tract-tracing utilizing manganese-enhanced magnetic resonance imaging (MEMRI). NMR Biomed. 17 595–601. 10.1002/nbm.942 [Google Scholar] Pautler R. G., Silva A. C., Koretsky A. P. (1998). In vivo neuronal tract tracing using manganese-enhanced magnetic resonance imaging. Magn. Reson.

 — Manganese-enhanced magnetic resonance imaging (MEMRI) holds exceptional promise for preclinical studies of brain-wide physiology in awake-behaving animals. The objectives of this review are to ...

This chapter will emphasize the methodological approaches towards the use of MEMRI in biological systems. The use of manganese ions (Mn(2+)) as an MRI contrast agent was introduced over 20 years ago in studies of Mn(2+) toxicity in anesthetized rats (1). Manganese-enhanced MRI (MEMRI) evolved in the late nineties when Koretsky and …

 — Manganese-enhanced magnetic resonance imaging has been well described in animal and human models showing the potential to assess myocardial calcium handling directly. 10–12 Here, manganese behaves as an analogue of calcium and is rapidly taken up by viable myocardium. 13, 14 We have shown that manganese …

 — Department of Radiology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital & Cancer Center, Kunming, China; Manganese-enhanced magnetic resonance imaging …

 — Magnetic resonance imaging (MRI) is an excellent non-invasive tool to investigate biological systems. The administration of the paramagnetic divalent ion …

Abstract. Manganese-enhanced magnetic resonance imaging (MEMRI) relies on contrasts that are due to the shortening of the T (1) relaxation time of tissue water protons that …

 — Nevertheless, current manganeseenhanced magnetic resonance imaging (MEMRI) tools have provided a viable method for visualizing cortical responses after evoked and/or spontaneous pain [2,3].

 — Manganese-enhanced magnetic resonance imaging (MEMRI) of rat brain after systemic administration of MnCl2: changes in T1 relaxation times during postnatal development. J. Magn. Reson. Imaging 25, 32–38. doi: 10.1002/jmri.20792. PubMed Abstract | CrossRef Full Text | Google Scholar.

Manganese-enhanced magnetic resonance imaging (MEMRI) NMR Biomed. 2004 Dec;17(8):527-31. doi: 10.1002/nbm.940. Authors Alan P Koretsky ... aimed at providing …

 — Manganese‐enhanced magnetic resonance imaging (MEMRI) Alan P. Koretsky. Corresponding Author. ... Andreas Hess, Manganese-Enhanced Magnetic …

 — In this study, we performed in vivo manganese-enhanced magnetic resonance imaging (MEMRI) to assess the regional cellular activity in the brains of αCaMKII HKO mice. The signal intensity of MEMRI 24 h after systemic MnCl2 administration reflects functional increases of Mn(2+) influx into neurons and glia via transport mechanisms, …

 — Manganese-enhanced magnetic resonance imaging (MEMRI) rose to prominence in the 1990s as a sensitive approach to high contrast imaging. Following the discovery of manganese conductance through calcium-permeable channels, MEMRI applications expanded to include functional imaging in the central nervous system (CNS) …

Manganese-enhanced magnetic resonance imaging (MEMRI) has therefore been used as a surrogate marker for cellular calcium handling and interest in its potential clinical applications has recently re-emerged, especially in relation to assessing cellular viability and myocardial function. Calcium homeostasis is central to myocardial contraction ...

Manganese-enhanced magnetic resonance imaging (MEMRI) Alan P. Koretsky* and Afonso C. Silva Laboratory of Functional and Molecular Imaging, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA Received 3 October 2004; Revised 6 October 2004; Accepted 6 October 2004

Studying Axonal Transport in the Brain by Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) Methods Mol Biol. 2022:2431:111-142. doi : 10.1007 ... these experimental systems reflected a valid picture of axonal transport in the opaque mammalian brain was unknown.Magnetic resonance imaging (MRI) provides a non-destructive …

 — Manganese (Mn 2+)-enhanced magnetic resonance (MR) imaging (MEMRI) in rodents offers unique opportunities for the longitudinal study of hippocampal structure and function in parallel with cognitive testing.However, Mn 2+ is a potent toxin and there is evidence that it can interfere with neuronal function. Thus, apart from causing adverse …

 — Introduction: Different techniques have been used to identify the brain regions that control sexual motivation and sexual behavior. However, the influence of sexual experience on the activation of these brain regions in the same subject is unknown. Using manganese-enhanced magnetic resonance imaging (MEMRI), we analyzed the …

 — Aims: To construct an automatic method for individual parcellation of manganese-enhanced magnetic resonance imaging (MEMRI) of rat brain with high accuracy, which could preserve the inherent voxel intensity and Regions of interest (ROI) morphological characteristics simultaneously. Methods and results: The transformation …

 — Background Transplantation of mononuclear cells (MNCs) has previously been tested as a method to induce therapeutic angiogenesis to treat limb ischemia in clinical trials. Non-invasive high resolution imaging is required to track the cells and evaluate clinical relevance after cell transplantation. The hypothesis that MRI can provide in vivo …